Childhood Acute lymphoblastic Leukaemia, commonly known as ALL, is a type of cancer in which the bone marrow produces way too many immature lymphocytes. The cancer spreads quickly through the blood to other parts of the body, and could lead to mortality if left untreated. Common symptoms are bone and joint pain, easy bleeding or bruising, loss of appetite and weight, fatigue, fever, paleness, red spots on skin and heaviness or pain below the ribs
HOW IS CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA DIAGNOSED?
The pediatritian will suggest Complete morphologic, immunologic, and genetic examination of the leukemic cells to establish the diagnosis of ALL. Routine laboratory studies in pediatric ALL include the following:
• CBC count
• Peripheral blood smear
• Serum chemistries (eg, potassium, phosphorus, calcium)
• Uric acid level
• LDH level
• Coagulation studies
HOW IS CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA TREATED?
Stem cell transplant and high intensity chemotherapy will be used in order to treat this disease. Targeted therapy and radiation on an immediate, emergency basis will also help in successful treatment.
DID YOU KNOW?
Because, cancers are rare in paediatrics, there are also several clinical trials that can be considered as a treatment option. These clinical trials, however, allow only those children who haven’t undergone any treatment as this increases the chances of success for the trial.