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Doctors for Alpha-1-antitrypsin in Siddharameshwar Nagar, Hubli-Dharwad
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Alpha-1 antitrypsin (AAT) is a deficiency that is an inherited condition and raises risks of lung and liver disease. The signs and symptoms may vary from individual to individual. The symptoms include shortness of breath, decreased capacity to exercise, wheezing, weight loss, fatigue, rapid heartbeat, etc. AAT is a protein that protects the lungs, if they are not in proper shape they get stuck in the liver cells and cannot reach the lungs leading to problematic situations.
HOW IS ALPHA-1-ANTITRYPSIN DIAGNOSED?
A specialist in the Pulmonologist department can diagnose the condition with the help of tests like the Alpha 1 Foundation as well as Protein Electrophoresis. Also, methods like nephelometric and immunoturbidimetric can be used to detect this deficiency.
HOW IS ALPHA-1-ANTITRYPSIN TREATED?
Lung affected patients are treated by intravenous infusion of alpha - 1- antitrypsin derived from donated human plasma. This is called augmentation therapy Augmentation therapy is not appropriate for liver affected patients. For such patients liver transplantation may be necessary Treatments also include inhaled forms of Alpha - 1- antitrypsin.
DID YOU KNOW?
Alpha- 1- antitrypsin deficiency was discovered after noting the absence of alpha -1 band on the protein electrophoresis in five of 1500 samples; three of the five patient samples were found to have developed emphysema at a young age.