D.N.B, Diplomate of National Board of Paediatrics, FACG, Fellowship in Gastroenterology & Hepatology, Fellowship in Gastroenterology, Hepatology & Nutrition, FIAP, FIMSA, Fellow, FRCPCH Fellow, M.B.B.S.
Gastroenterologist - Specializes in Treatment of Pyoderma Gangrenosum
Pyoderma gangrenosum (PG) is a rare and serious skin disease in which a painful nodule or pustule breaks down to form a progressively enlarging ulcer. The name relates to the appearance of the ulcers, which have a purulent surface ('pyoderma') and a blue-black edge ('gangrenosum'). However, there is neither infection nor gangrene involved.
HOW IS PYODERMA GANGRENOSUM DIAGNOSED?
Pyoderma gangrenosum is diagnosed by its characteristic appearance. There is no specific test. The wound should be swabbed and cultured for micro-organisms, but these are not the cause of pyoderma gangrenosum. Biopsy may be necessary to rule out other causes of ulceration. Pyoderma gangrenosum characteristically results in a neutrophilic inflammatory infiltrate but this is not always present. The pathergy test is usually positive (a skin prick test causing a papule, pustule or ulcer).
HOW IS PYODERMA GANGRENOSUM TREATED?
Treatment for Pyoderma Gangrenosum depends on what type you are suffering from. Usually doctors prefer using a stepwise approach here that includes medicines like corticosteroids and ciclosporin. Other kinds of immunosuppressive agents are also used here.
DID YOU KNOW?
The disease was identified in 1930. It affects approximately 1 person in 100,000 in the population. Though it can affect people of any age, it mostly affects people in their 40s and 50s.