The presence of excess orotic acid in the urine is known as Orotic Aciduria. This condition is a form of anaemia known as megaloblastic anaemia. In this disorder the body cannot produce cannot produce an enzyme known as YMP synthetase. In addition to the increased levels of orotic acid patients with this disorder could also be mentally and physically retarded.
HOW IS OROTIC ACIDURIA DIAGNOSED?
A general physician will require urine tests to diagnose the condition. Genetic testing helps as well as the condition is often considered to be hereditary in nature.
HOW IS OROTIC ACIDURIA TREATED?
Treatment for Orotic Aciduria is done via internal medicines. Other mode of treatment here include cytidine monophosphate and uridine monophosphate that is known to reduce the levels of orotic acid in the patients. For people who are suffering from the hereditary form of the same, Uridine triacetate can be used.
DID YOU KNOW?
Orotic Aciduria is an extremely rare and inherited disorder.