Leigh Syndrome is a rare genetic neurometabolic disease that is characterized by the degeneration of the central nervous system. The symptoms of Leigh Syndrome usually surface from ages of 3 months to 2 yrs. Symptoms of Leigh Syndrome are:
• Loss of previously acquired motor skills in infants
• Loss of head control
• Poor sucking ability
• Profound loss of appetite
• Continuous crying
• Possible seizure
• Developmental delays
• Generalized weakness
• Muscle spasms
• Respiratory problems
HOW IS LEIGH SYNDROME DIAGNOSED?
The diagnosis of Leigh syndrome may be confirmed by a thorough clinical evaluation and a variety of specialized tests, particularly advanced imaging techniques. Magnetic resonance imaging (MRI) or computed tomography (CT) scans of the brain may reveal abnormal areas in certain parts of the brain. An MRI uses a magnetic field and radio waves to produce cross-sectional images of particular organs and bodily tissues. During CT scanning, a computer and x-rays are used to create a film showing cross-sectional images of certain tissue structures.
HOW IS LEIGH SYNDROME TREATED?
The most common treatment of Leigh Syndrome is the administration of thiamine (Vitamin B1) or thiamine derivatives.
DID YOU KNOW?
Leigh Syndrome is, as a matter of fact, suggested by clinical findings and confirmed with laboratory and genetic testing.