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Overview

Sildura 8 Combipack

Manufacturer :  Sun Pharmaceutical Industries Ltd
Medicine Composition :  Silodosin, Dutasteride
Prescription vs OTC : Prescription by Doctor required

About Sildura 8 Combipack

Sildura 8 Combipack falls under a category of drugs known as alpha blockers. This medication is used to treat enlarged prostate (benign prostatic hyperplasia or BPH). It functions by relaxing the prostate and bladder muscles allowing greater urine flow. Sildura 8 Combipack is primarily used by men. It reduces signs and symptoms of BPH.

On using this medication you may experience side effects such as dizziness, decrease in sexual libido, skin rash, hives, discoloration of skin or eyes, chest pain, swelling of body parts or darkening of the urine and painful erection. Seek medical help if you experience any allergic reaction.

Don’t use Sildura 8 Combipack if you are allergic to any ingredient contained within it, you have kidney/liver disorders. Before using this medication notify your doctor if you have/are:

  • Taking any prescription or non-prescription drugs,
  • Allergic to any food/medicine/substance,
  • Blood pressure or
  • Prostate cancer,
  • Scheduled for any surgery soon,
  • Pregnant or are planning to become pregnant or are breastfeeding a baby (for women).

The dosage for this medication should be determined by the doctor. The usual dose in adults for treating prostatic hyperplasia is 8 mg to be taken orally once daily along with a meal.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the uses of Sildura 8 Combipack

    • Benign Prostatic Hyperplasia

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the contraindications of Sildura 8 Combipack ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the side effects of Sildura 8 Combipack ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    Key highlights of Sildura 8 Combipack

    • Is It safe with alcohol?

      Taking Sildura 8 Combipack with alcohol may have additive effects in lowering your blood pressure. You may experience a headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

    • Are there any pregnancy warnings?

      Sildura 8 Combipack is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      It may cause dizziness. Exercise caution if you have to drive or operate a machinery.

    • Does this affect kidney function?

      Caution must be taken while using this medicine in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

    • Does this affect liver function?

      Caution must be taken while using this medicine in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the substitutes for Sildura 8 Combipack ?

    Below is the list of medicines, which have the same composition, strength and form as Sildura 8 Combipack , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Silodosin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    How does this medication work?

    Sildura 8 Combipack works as an antagonist of the alpha-1 adrenoreceptor selective for the prostrate. It binds to and blocks these receptors which lowers intraurethral pressure, relaxes smooth muscles and improves urine flow.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

      What are the interactions of Sildura 8 Combipack ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Alcohol consumption should be limited during the course of medication.
      • Interaction with Medicine

        Sildura 8 Combipack interacts with amitriptyline, alprazolam, nefazodone and clotrimazole.
      • Interaction with Disease

        Patients suffering from kidney or liver disease should not use the medication.

      FAQs about Sildura 8 Combipack

      • Ques : Can Sildura 8 Combipack cause erectile dysfunction?

        Ans : Sildura 8 Combipack usually does not affect erectile function. However, Sildura 8 Combipack may cause other sexual problems like ejaculatory dysfunction and failure to ejaculate.

      • Ques : When should I take Sildura 8 Combipack?

        Ans : It is usually advised to take the dose of Sildura 8 Combipack daily with a meal. Prefer taking it at the same time of the day. In patients with any kidney impairment, the dose is reduced by the doctor.

      • Ques : What is Sildura 8 Combipack used for?

        Ans : Sildura 8 Combipack is a medicine given for the treatment of difficulty in urination, urinary dribbling, a strong urge to urinate, and frequent urination during the night. It is also used to relieve other symptoms associated with benign enlargement of the prostate gland.

      • Ques : Does Sildura 8 Combipack lower blood pressure?

        Ans : Yes, Sildura 8 Combipack may cause a drop in blood pressure. This most commonly occurs while taking the first dose of this medicine. Hence, you should be cautious while driving, operating any machinery, or doing any important work during the initial days of treatment. Consult your doctor before you start taking this medication.

      • Ques : Can I undergo cataract surgery while taking Sildura 8 Combipack?

        Ans : In some cases, Sildura 8 Combipack has shown specific side effects on the eyes. It has been observed that during an eye surgery the iris tends to get floppy and pupil size becomes small in patients taking Sildura 8 Combipack. This makes the operation difficult and tedious. Hence, you should always inform your eye specialist about any history related to the use of Sildura 8 Combipack.

      References

      • Silodosin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 15 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/silodosin

      • Silodosin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 15 June 2022].Available from:

        https://go.drugbank.com/drugs/DB06207

      • DUTASTERIDE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 15 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DUTASTERIDE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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