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Overview

Sibutramine

Prescription vs OTC : Prescription by Doctor required

About Sibutramine

Sibutramine, an oral anorexiant is used to treat obesity with reduced calorie diet and exercise. It works by the regulation of the neurotransmitters in the brain that reduce hunger and hence help in weight maintenance. A reduction of 5-10% of weight from their baseline is observed in patients medicated with Sibutramine.

Sibutramine should not be used if the person is above 65 years of age or has taken monoamine oxidase inhibitor, selective serotonin inhibitor or another appetite suppressant within the last 14 days. Moreover, persons with severe high blood pressure, heart or blood vessel problems, eating disorder, severe liver or kidney problems, transient ischemic attack or stroke should also avoid taking the medicine.

Initial dosage of Sibutramine includes oral ingestion of 10mg once a day. In cases of insufficient weight loss, the dose might be increased up to 15mg once a day. However, an increase in dose more than 15mg is not recommended. This drug should not be administered to individuals with severe renal dysfunction.

Side effects include insomnia, constipation, pharyngitis, nausea, arthralgia, nervousness, rhinitis, sinusitis, dyspepsia, headache, dry mouth, asthenia, anorexia, back pain, increased appetite, flu syndrome and accidental injury.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

    What are the uses of Sibutramine

    • Obesity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

    What are the side effects of Sibutramine ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

    Key highlights of Sibutramine

    • Is It safe with alcohol?

      Sibutrim 10mg capsule may cause excessive drowsiness and calmness with alcohol.

    • Are there any pregnancy warnings?

      Sibutrim 10mg capsule may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Sibutramine, skip it and continue with your normal schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

    Medicines containing Sibutramine

    Below is the list of medicines, which contains Sibutramine as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

    How does this medication work?

    Sibutramine acts as an appetite suppressant that functions by enhancing the levels of chemical messengers serotonin and norepinephrine in the brain. Sibutramine stimulates a feeling of satiety and low appetite by hindering the reuptake of these neurotransmitters.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Bariatric Surgery before using this medicine.

      What are the interactions of Sibutramine ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

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        Benadryl Dr Dry Cough Active Relief Syrup

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        Hytram 100Mg Injection

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      References

      • Sibutramine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/sibutramine

      • Sibutramine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 9 June 2022].Available from:

        https://go.drugbank.com/drugs/DB01105

      • SIBUTRAMINE capsule,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=SIBUTRAMINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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