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Overview

Nikoran 5Mg Tablet

Manufacturer :  Torrent Pharmaceuticals Ltd
Medicine Composition :  Nicorandil
Prescription vs OTC : Prescription by Doctor not required

About Nikoran 5Mg Tablet

Nikoran 5Mg Tablet is a vasodilatory drug. It treats angina chest pain. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. This medication is used to treat other heart conditions also.

On using Nikoran 5Mg Tablet you may experience side effects such as rapid or irregular heartbeat, swelling, darkening of urine, dizziness, headache, nausea, fatigue, a decrease in blood pressure levels, flushes, skin rash, high potassium levels, muscle pain or stomach pain. Notify your physician if you face any of these effects.

Before using this medication tell your doctor if you are allergic to any of the ingredients contained within Nikoran 5Mg Tablet, having any other allergies, already taking any medications, have low blood pressure, skin/ mouth ulcers, heart problems or pulmonary oedema, are pregnant or are breastfeeding a baby.

The dosage should be prescribed by your doctor based on your medical history and current condition. The usual dose in adults is about 10 mg twice a day which may be increased to 20 mg depending on your response.

    What are the uses of Nikoran 5Mg Tablet

    What are the contraindications of Nikoran 5Mg Tablet ?

    What are the side effects of Nikoran 5Mg Tablet ?

    Key highlights of Nikoran 5Mg Tablet

    • Is It safe with alcohol?

      It is unsafe to consume alcohol while taking this medicine.

    • Are there any pregnancy warnings?

      This medicine is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

    • Are there any breast-feeding warnings?

      This medication is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    • Is it safe to drive while on this medicine?

      This medicine might affect the consciousness of the patient. Thus driving must be avoided while taking Nikoran 5Mg Tablet.

    What are the substitutes for Nikoran 5Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Nikoran 5Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Nicorandil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

    • Are there any overdose instructions?

      In case of overdose, consult your doctor.

    How does this medication work?

    This medication works following a dual mechanism. Firstly, it activates the ATP sensitive potassium channel, leading to vascular smooth muscle hyperpolarization. Secondly, it triggers guanylate cyclase to enhance the production of cyclic GMP, thereby activating protein kinase G. Therefore, GTPase RhoA is inhibited and Rho-kinase activity is decreased. As a result, the myosin phosphate activity is accelerated and the calcium sensitivity of the smooth muscle is reduced. Owing to its nitrate property, nicorandil works as a vasodilator.

      What are the interactions of Nikoran 5Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medication interacts with Corticosteroids, Riociguat, NSAIDs, Phosphodiesterase 5 (PDE) inhibitors, and Vasodilators.
      • Interaction with Disease

        This medication interacts with Gastrointestinal Disorders.

      FAQs about Nikoran 5Mg Tablet

      • Ques : What is Nikoran 5Mg Tablet?

        Ans : This is a medication which has Nicorandil as an active element present. It performs its action by calming the blood vessels of the heart and increasing the supply of blood and oxygen to the heart and decreases pain.

      • Ques : What are the uses of Nikoran 5Mg Tablet?

        Ans : This is a medication, which is used for the treatment and prevention from conditions such as Angina pectoris and Acute coronary syndrome.

      • Ques : What are the Side Effects of Nikoran 5Mg Tablet?

        Ans : This is a medication which has some commonly reported side effects such as Hypersensitivity, Yellowing of skin and eyes, Increase in the potassium levels, Watery eyes, Gastric Ulcer, Hypotension, Nausea and vomiting, etc.

      • Ques : What are the instructions for storage and disposal Nikoran 5Mg Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Nicorandil- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 May 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/nicorandil

      • Nicorandil- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 23 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB09220

      • Nicorandil 10mg Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 23 May 2019]. Available from:

        https://www.medicines.org.uk/emc/product/652/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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