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Overview

Moxigram 0.5% Eye Drops

Manufacturer :  Micro Labs Ltd
Medicine Composition :  Moxifloxacin
Prescription vs OTC : Prescription by Doctor required

About Moxigram 0.5% Eye Drops

Moxigram 0.5% Eye Drops is primarily prescribed for the treatment of mild to moderate community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, and acute bacterial sinusitis.

Moxigram 0.5% Eye Drops is a drug that belongs to the cluster of quinolone antibiotics that is administered to remedy bacterial infections. However, this medicine will not work for viral infections such as flu and the common cold. This antibiotic works by preventing the growth and further infestation of bacteria.

Remember that using an antibiotic repetitively for trivial issues or for problems not caused by bacteria will lead the bacteria to become resistant to that antibiotic. Thus the antibiotic will lose its efficacy over a period of time. You must drink sufficient fluids unless of course advised otherwise.

The length of the treatment plan and dosage of Moxigram 0.5% Eye Drops will depend upon the severity of the condition. It is advised to take this drug about 4 to 8 hours prior to the intake of other minerals/vitamins or products containing magnesium or aluminium such as antacids.

For best results, take this medicine at regular intervals every day. Finish the course of the antibiotic even if your condition gets better; this is because stopping the intake of an antibiotic prematurely will result in the relapse of the infection and the bacteria turning antibiotic-resistant over a period of time.

This medicine may cause some of the side effects include nausea, sore throat, dizziness, lightheadedness, diarrhea, headaches and difficulty in sleeping. Although rare, a severe intestinal condition ‘Clostridium Difficile Diarrhea could develop.

Let your doctor know without any delay should you experience persistent diarrhoea or notice the presence of blood or mucous in the stool. Take note that prolonged intake of this drug, beyond the prescribed time limit, may result in the formation of white patches in the mouth (oral thrush) or a new yeast infection that could manifest itself in the form of vaginal discharges.

Potential symptoms of overdose may include CNS excitation, seizures, QT prolongation, and arrhythmias (including torsade de pointes). Patients should be monitored by continuous EKG in the event of an overdose. Management is supportive and symptomatic. Not removed by dialysis.

May be taken with or without food. Drink plenty of fluids. Avoid direct exposure to direct sunlight during therapy and for several days following. Do not take antacids within 4 hours before or 8 hours after dosing.

Contact your physician immediately if signs of allergy occur. Contact your physician immediately if signs of tendon inflammation or pain occur. Do not discontinue therapy until your course has been completed. Take a missed dose as soon as possible, unless it is almost time for your next dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Moxigram 0.5% Eye Drops

    • Community Acquired Pneumonia

    • Chronic Bronchitis

    • Sinusitis

    • Skin And Structure Infection

    • Intra-Abdominal Infections

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Moxigram 0.5% Eye Drops ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Moxigram 0.5% Eye Drops ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Moxigram 0.5% Eye Drops

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 12 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 0.5 to 4 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended for women who are breastfeeding due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    • Is It safe with alcohol?

      Consumption of alcohol is found to be safe if taken along with this medication.

    • Is it safe to drive while on this medicine?

      This medication can cause side effects that may affect the alertness of the patient. Thus driving should be avoided, if you are taking this medication.

    • Does this affect kidney function?

      This medicine is found to be safe to use in patients with kidney disease. Adjustment of dose is not needed. Inform your doctor if you face any issue.

    • Does this affect liver function?

      No dosage adjustment is required in mild hepatic insufficiency (Child-Pugh Class A). Not recommended in patients with moderate to severe hepatic insufficiency.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Moxigram 0.5% Eye Drops ?

    Below is the list of medicines, which have the same composition, strength and form as Moxigram 0.5% Eye Drops , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Moxigram 0.5% Eye Drops approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    Moxigram 0.5% Eye Drops is a fluoroquinolone antibiotic that works by inhibiting the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. This interferes with the bacterial cell replication and repair leading to cell death.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Moxigram 0.5% Eye Drops ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        • Drugs which prolong QT interval (including Class Ia and Class III antiarrhythmics, erythromycin, cisapride, antipsychotics, and cyclic antidepressants) are contraindicated with Moxigram 0.5% Eye Drops.
        • Metal cations (magnesium, aluminum, iron, and zinc) bind quinolones in the gastrointestinal tract and inhibit absorption (by up to 98%). Antacids, electrolyte supplements, sucralfate, quinapril, and some didanosine formulations should be avoided. Moxigram 0.5% Eye Drops should be administered 4 hours before or 8 hours after these agents.
        • Antineoplastic agents may decrease the absorption of quinolones.
        • Cimetidine, and other H2 antagonists may inhibit renal elimination of quinolones.
        • Digoxin levels may be increased in some patients by quinolones; monitor for increased effect/concentrations.
        • Foscarnet has been associated with an increased risk of seizures with some quinolones.
        • Loop diuretics: Serum levels of some quinolones are increased by loop diuretic administration. May diminish renal excretion.
        • NSAIDs: The CNS stimulating effect of some quinolones may be enhanced, resulting in neuroexcitation and/or seizures. This effect has not been observed with Moxigram 0.5% Eye Drops.
        • Probenecid: Blocks renal secretion of quinolones, increasing concentrations.
        • Warfarin: The hypoprothrombinemic effect of warfarin is enhanced by some quinolone antibiotics. No significant effect has been demonstrated for Moxigram 0.5% Eye Drops, however, monitoring of the INR during concurrent therapy is recommended by the manufacturer.
      • Interaction with Disease

        Central Nervous System Depression

        If you suffer from CNS disorder and you take Moxigram 0.5% Eye Drops, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine containing products like coffee, chocolates and energy drinks.

        Qt Prolongation

        Avoid using Moxigram 0.5% Eye Drops if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

        Colitis

        Avoid taking Moxigram 0.5% Eye Drops if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
      • Interaction with Food

        Information not available.

      FAQs about Moxigram 0.5% Eye Drops

      • Ques : Can the use of Moxigram 0.5% Eye Drops increase the risk of muscle damage?

        Ans : Yes, the use of this medicine might increase the risk of muscle damage, commonly in the ankle (Achilles tendon). People of all ages can experience muscle damage who take Moxigram 0.5% Eye Drops.

      • Ques : Can the use of Moxigram 0.5% Eye Drops cause diarrhea?

        Ans : Yes, the use of this medication can cause diarrhea. Being an antibiotic, this drug helps in killing harmful bacteria. If, in case, you are experiencing severe diarrhea, consult your doctor.

      • Ques : Can I stop taking Moxigram 0.5% Eye Drops when I feel better?

        Ans : No, you must not stop taking this medication. It is suggested to complete the full course of treatment even if you feel better.

      • Ques : How long do I need to use Moxigram 0.5% Eye Drops before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Moxigram 0.5% Eye Drops?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Moxigram 0.5% Eye Drops empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Moxigram 0.5% Eye Drops?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Moxifloxacin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/moxifloxacin

      • Moxifloxacin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 31 May 2022].Available from:

        https://go.drugbank.com/drugs/DB00218

      • MOXIFLOXACIN Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=MOXIFLOXACIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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