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Overview

Enalapril

Prescription vs OTC : Prescription by Doctor required

About Enalapril

An angiotensin converting enzyme (ACE) inhibitor, Enalapril helps in the treatment of hypertension, also known as high blood pressure, both in adults as well as children above a month old. The drug also effectively treats adults with congestive heart failure. Moreover, it is prescribed to patients with ventricle disorder. This disorder can affect the hearts capacity of pumping blood to other parts of the body.

A few facts about the drug should be established before use. For instance the drug is not meant for consumption by pregnant women. If you are taking the drug and become pregnant, discontinue it after informing your doctor. The drug is not meant for breastfeeding mothers as well, because it can harm the child. Thus new mothers on Enalapril are discouraged from nursing their child. It should also be avoided if you have angioedema or are allergic to ACE inhibitors. If you are suffering from health conditions like diabetes or kidney problems do not take the drug in combination with aliskiren. It is best to inform the doctor about any history of stroke or blood clot as well as instances of electrolyte imbalance.

Enalapril should be taken as per directions on the prescription and the doctor’s orders. It can either be taken with food or before. The drug is available in both liquid and tablet form and should be stored at normal temperature. Heat as well as moisture should not affect the drug.

You may experience a number of side effects of the drug, which may include tiredness, excessive coughing, light-headedness. Some severe side effects are slow or pounding heartbeat, fever with chills, jaundice, bruising etc. In case you experience any of the severe side effects or any other symptoms get medical help immediately. The dosage of Enalapril for adults may vary from 5 mg – 40 mf daily.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the uses of Enalapril

    • Hypertension

      Enalapril is used to treat an increase in the blood pressure caused by genetic and/or environmental factors.

    • Congestive Heart Failure (Chf)

      Enalapril is used in the treatment of congestive heart failure which is a type of heart disease, charecterized by thickening of the walls of the left ventricle.

    • Left Ventricular Dysfunction

      Enalapril is used in the treatment of left ventricular dysfunction, which is a type of heart disease that lowers the pumping capacity of the heart.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the contraindications of Enalapril ?

    • Allergy

      Avoid taking this medicine, if you have a known allergy to it or any medicine of the same class.

    • Aliskiren

      Use of these medicines is not recommended in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the side effects of Enalapril ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Key highlights of Enalapril

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 6 hours after an intravenous dose and 12-24 hours after an oral dose.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 15 minutes after an intravenous injection and 1 hour after an oral dose.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for breastfeeding women.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Where is the Enalapril approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Medicines containing Enalapril

    Below is the list of medicines, which contains Enalapril as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    How does this medication work?

    This medication works by inhibiting an enzyme called angiotensin-converting enzyme which results in decreased plasma angiotensin II and decreased aldosterone secretion. Thus prevents the blood vessel constriction, water reabsorption and helps in lowering the blood pressure.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

      What are the interactions of Enalapril ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        You should avoid the consumption of alcohol while taking this medicine as it may cause dizziness, headache, and changes in heart rate. Avoid driving or operating heavy machinery if you have these symptoms.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Losartan

        Use of these medicines is not recommended as it may increase the risk of kidney impairment and low blood pressure. You may experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.

        Corticosteroids

        The desired effect of Enalapril will not be obtained if these medicines are taken together. This interaction is more likely to happen if dexamethasone is taken for more than 1 week. Inform the doctor if you have a sudden weight gain, swelling of hands and feet. If coadministration is needed then suitable dose adjustments are to be made under the doctor's supervision. Regular monitoring of blood pressure and kidney function tests are to be performed.

        Aliskiren

        Use of these medicines is not recommended especially in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min. You experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.

        Insulin

        The effect of insulin will increase if these medicines are taken together. You may experience dizziness, headache, sweating if these medicines are taken together. Regular monitoring of blood glucose levels is needed. Suitable dose adjustments or an alternate medicine should be considered under the doctor's supervision.

        Diclofenac

        The desired effect of Enalapril will not be obtained if these medicines are taken together. The risk of kidney impairment will increase if these medicines are taken together especially in elderly population or having pre-existing kidney disease. Inform the doctor if you have an increased or decreased urination and unexplained weight gain or weight loss. Regular monitoring of blood pressure and kidney function tests are to be performed.
      • Interaction with Disease

        Angioedema

        Enalapril is not recommended in patients with a history of Angioedema or a family history of Angioedema. Any symptoms of swelling of face, lips, and eyes should be informed to the doctor. If necessary, an alternate medicine should be considered based on the clinical condition.
      • Interaction with Food

        Food

        Information not available.

      References

      • Enalapril-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/enalapril

      • Enalapril-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00584

      • Enalapril Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Enalapril

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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