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Overview

Duet 625 Tablet

Manufacturer :  Lupin Ltd
Medicine Composition :  Amoxycillin, Clavulanic Acid
Prescription vs OTC : Prescription by Doctor not required

About Duet 625 Tablet

Duet 625 Tablet is prescribed for the treatment of otitis media, sinusitis, and infections caused by susceptible organisms involving the lower respiratory tract, skin and skin structure, and urinary tract. This is a combination medication that has Amoxycillin and Clavulanic Acid as active ingredients. Its spectrum is the same as amoxicillin with additional coverage of beta-lactamase.

The extended coverage Duet 625 Tablet is due to its combination, which makes it a useful alternative when amoxicillin resistance is present and patients cannot tolerate alternative treatments.

Duet 625 Tablet is an antibiotic belonging to the class of penicillin antibiotic that helps in the treatment of bacterial infections. The medicine works against the synthesis of the bacteria. It also treats conditions like gonorrhoea, tonsillitis, infection in the eye, middle ear or nose. It is important that you do not consume this tablet for cold, flu or other viral infections.

Symptoms of penicillin overdose include neuromuscular hypersensitivity (agitation, hallucinations, asterixis, encephalopathy, confusion, and seizures) and electrolyte imbalance with potassium or sodium salts, especially in renal failure.

Hemodialysis may be helpful to aid in the removal of the drug from the blood, otherwise most treatment is supportive or symptom directed.

Take entire prescription, even if you are feeling better. Take at equal intervals around-the-clock; may be taken with milk, juice, or food. You may experience nausea or vomiting (small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may help).

If using oral contraceptives, use additional contraceptive measures; amoxicillin may reduce the effectiveness of your oral contraceptive. Report rash; unusual diarrhoea; vaginal itching, burning, or pain; unresolved vomiting or constipation; fever or chills; unusual bruising or bleeding; or if the condition being treated worsens or does not improve by the time prescription is completed.

    What are the uses of Duet 625 Tablet

    What are the contraindications of Duet 625 Tablet ?

    What are the side effects of Duet 625 Tablet ?

    Key highlights of Duet 625 Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average of 1.5 to 2 hours.

    • What is the onset of action?

      The effect of this medicine can be observed within 1-2 hours of administration.

    • Are there any pregnancy warnings?

      This medication is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

    • Is it habit forming?

      No habit forming tendencies have been reported.

    • Are there any breast-feeding warnings?

      This medication is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

    • Is It safe with alcohol?

      It is advisable to limit the consumption of alcohol while eating these tablets because the effects of alcohol while eating this medicine are unknown. It is also advisable to consult the doctor while eating Duet 625 Tablet.

    • Is it safe to drive while on this medicine?

      It has the effect of drowsiness on the patient and can make him/her sleep. Hence, it is not advisable to drive or operate heavy machinery during this process. It is also not advisable to do any other job that requires alertness while consuming Duet 625 Tablet.

    • Does this affect kidney function?

      It can cause severe side effects in the kidney if they already suffer with an abnormal functioning of the kidney. Convulsions can occur in such patients which is why and adjustment in the dose is necessary for such patients.

    • Does this affect liver function?

      Patients with an impairment in the normal liver function must ingest the medicine with great caution. The regular monitoring of liver enzyme levels during and after the treatment is necessary.

    What are the substitutes for Duet 625 Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Duet 625 Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      One should contact the doctor immediately if an overdose is suspected.

    How does this medication work?

    This medicine is a combination of Amoxycillin and Clavulanic acid. Amoxycillin is an extended spectrum Penicillin class of antibiotic and inhibits the transfer of a peptide group in the transpeptidation process. As a result the bacterium is not able to build cell walls and is killed. Whereas, Clavulanic acid is a drug of beta-lactamase inhibitor class, which reduces resistance and potentiates the activity of Amoxycillin against bacteria.

      What are the interactions of Duet 625 Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Duet 625 Tablet is used to cure grave bacterial infections, which is why it is recommended not to consume alcohol during the treatment. Although alcohol doesn’t interact with Duet 625 Tablet, it is essential to let the body heal and gain plenty of fluids which is why alcohol must be rescinded.

      • Interaction with Medicine

        Duet 625 Tablet can interact with certain medicines or supplements to cause severe side effects. You must discuss the medicines you currently are taking with the doctor so that he/she can prescribe your substitutes.
        • Doxycycline, methotrexate, warfarin, ethinylestradiol and live vaccines are some of the medicines that interact with this medication to cause adverse side effects.
        • Decreased effect: Efficacy of oral contraceptives may be reduced.
        • Increased effect: Disulfiram, probenecid may increase amoxicillin levels, increased effect of anticoagulants.
        • Increased toxicity: Allopurinol theoretically has an additive potential for amoxicillin rash.
      • Interaction with Disease

        In patients with renal impairment, doses and/or frequency of administration should be modified in response to the degree of renal impairment; high percentage of patients with infectious mononucleosis have developed rash during therapy; a low incidence of cross-allergy with cephalosporins exists; incidence of diarrhea is higher than with amoxicillin alone. Hepatic dysfunction, although rare, is more common in elderly and/or males, and occurs more frequently with prolonged treatment.
      • Interaction with Food

        Duet 625 Tablet must be taken with food to reduce side effects and digestion problems, and it may be taken every 8 to 12 hours, as prescribed. Some people take it before food or after food as advised by their doctor.

      FAQs about Duet 625 Tablet

      • Ques : What is Duet 625 Tablet?

        Ans : Duet is a medication which has Amoxycillin and Clavulanic Acid as active elements present in it.

      • Ques : What are the uses of Duet 625 Tablet?

        Ans : Duet Tablet is used for the treatment and prevention from conditions such as Ear Infection (Otitis Media), Nose Infection (Sinusitis), Throat Infection (Tonsillitis/Pharyngitis), and Lower Respiratory Tract Infection.

      • Ques : What are the Side Effects of Duet 625 Tablet?

        Ans : Allergic Skin Reaction, Diarrhea, Fever, Joint pain, Skin yellowing, Easy bruising and bleeding, Heavy menstrual bleeding, Tooth discoloration, Nausea or vomiting, Altered sense of taste, etc are possible side effects.

      • Ques : What are the instructions for storage and disposal Duet 625 Tablet?

        Ans : Duet 625 tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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