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Overview

Cefalexin

Prescription vs OTC : Prescription by Doctor required

About Cefalexin

Cefalexin is used for the treatment of various infections that are caused by bacteria. It includes infections in the respiratory tract, bone infections, middle ear infection, urinary tract infection, skin infections and sore throat. It can also be used for preventing endocarditis (heart valve inflammation) that is caused by an infection.

Cefalexin belongs to the drug group known as cephalosporin (antibiotic). It interferes in the formation of the cell walls of the bacteria. This results in the rupturing of the walls and hence kills the bacteria. The medication is available in tablet and liquid form for oral consumption.

The dosage of Cefalexin depends on your age, general health, the condition for which the treatment is being done and its severity, as well as your body’s reaction to the first dose. Take the dosages as directed by the doctor. If you miss a dose, you can have it as soon as you remember about it, but skip it if the time for your next scheduled dose is near. Do not take two doses together to make up for a missed one as overdosing can lead to nausea, vomiting, stomach aches, diarrhea and blood in urine.

The common side effects of Cefalexin include indigestion, stomach pain and inflammation or irritation in the lining of the stomach. Being mild in nature, they tend to go away in a few days. There are some serious side effects though that may occur, which would require immediate medical help:

  • A serious allergic reaction, the symptoms of which may include hives, swelling of the face and lips or trouble breathing
  • Oral thrush or a yeast infection; symptoms include white patches inside the mouth and changes in vaginal discharge
  • Persistent diarrhea with the presence of blood or mucus in stool

Cefalexin can pass on to a new born baby by the mother through breastfeeding and affect the baby. Therefore it is important to inform your doctor regarding the same before taking the medicine. Pregnant women or those planning to get pregnant must also inform their doctor about their condition beforehand.

Take as directed, at regular intervals around-the-clock (with or without food). Chilling oral suspension improves flavor (do not freeze). Complete full course of medication, even if you feel better. Drink 2-3 L fluid/day.

If diarrhea occurs, yogurt or buttermilk may help. May cause false-positive test with Clinitest®; use another form of testing. May interfere with oral contraceptives; additional contraceptive measures are necessary. Report severe, unresolved diarrhea; vaginal itching or drainage; sores in mouth; blood, pus, or mucus in stool or urine; easy bleeding or bruising; unusual fever or chills; rash; or respiratory difficulty.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Cefalexin

    • Bacterial Infections

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Cefalexin ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Cefalexin ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Cefalexin

    • How long is the duration of effect?

      This medicine is excreted in urine and the effect lasts for a duration of 4 to 5 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 hour after oral administration.

    • Are there any pregnancy warnings?

      This medicine should be taken during pregnancy only if it is clearly needed under doctor's supervision.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This medicine is known to excreted in human breast milk. It should be taken only if clearly needed under doctor's supervision. Monitoring of undesired effects like diarrhea or thrush is necessary.

    • Is It safe with alcohol?

      It is found to be safe to consume alcohol while taking this medicine.

    • Is it safe to drive while on this medicine?

      Usually this medicine does not affect the alertness of the patient.

    • Does this affect kidney function?

      Caution must be taken in patient with kidney disease, Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Caution must be taken in patient with liver disease, Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Cefalexin approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Medicines containing Cefalexin

    Below is the list of medicines, which contains Cefalexin as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medicine works as a bactericidal by inhibiting the bacterial cell wall synthesis by binding to penicillin-binding proteins which inhibits the growth and multiplication of bacteria. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Cefalexin ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Positive direct Coombs', false-positive urinary glucose test using cupric sulfate (Benedict's solution, Clinitest®, Fehling's solution), false-positive serum or urine creatinine with Jaffé reaction, false-positive urinary proteins and steroids.
      • Interaction with Food

        Peak antibiotic serum concentration is lowered and delayed, but total drug absorbed is not affected; take on an empty stomach. If GI distress, take with food.
      • Interaction with Disease

        • Increased effect: High-dose probenecid decreases clearance.
        • Increased toxicity: Aminoglycosides increase nephrotoxic potential.

        FAQs about Cefalexin

        • Ques : What is Cefalexin and is used for?

          Ans : Cefalexin is an antibiotic. Cefalexin is used in the treatment of bacterial infection.

        • Ques : Can the use of Cefalexin cause diarrhea?

          Ans : Yes, the use of Cefalexin can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea persists, talk to your doctor about it.

        • Ques : Is Cefalexin safe?

          Ans : Cefalexin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

        • Ques : What if Cefalexin doesn't work?

          Ans : Talk to your doctor if Cefalexin doesn't seem to work for you. Your doctor may increase the dose of Cefalexin or switch you to an alternate option, which may work for you.

        • Ques : What if I don't get better after using Cefalexin?

          Ans : Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

        • Ques : Can I stop taking Cefalexin when my symptoms are relieved?

          Ans : No, do not stop taking Cefalexin and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

        References

        • Cefalexin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 31 May 2022].Available from:

          https://druginfo.nlm.nih.gov/drugportal/name/cefalexin

        • Cefalexin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 31 May 2022].Available from:

          https://go.drugbank.com/drugs/DB00567

        Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

        Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

        Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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        Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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        Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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