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Dr. Shailesh Puntambekar

Oncologist, Delhi

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Dr. Shailesh Puntambekar Oncologist, Delhi
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I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning....more
I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning.
More about Dr. Shailesh Puntambekar
Dr. Shailesh Puntambekar is a renowned Oncologist in Rajender Nagar, Delhi. You can consult Dr. Shailesh Puntambekar at Dr. Shailesh Puntambekar@BLK Super Speciality Hospital in Rajender Nagar, Delhi. Book an appointment online with Dr. Shailesh Puntambekar and consult privately on Lybrate.com.

Lybrate.com has an excellent community of Oncologists in India. You will find Oncologists with more than 41 years of experience on Lybrate.com. You can find Oncologists online in Delhi and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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All About Melanoma

MD, DNB, FIDP, FIL
Dermatologist, Mumbai
All About Melanoma

Melanoma is a condition which mainly indicates a severe malfunction of the melanocytes or the melanin producing cells of the body. These cells are responsible for giving you your skin colour, tone and complexion. Usually, a person suffering from melanoma will have many normal and irregular moles as well as melanoma in the eye and digestive tracts too.

Some general facts on melanoma are mentioned below:

  1. Melanoma is common in young women and causes many deaths.

  2. More than one million new instances of skin cancer or melanoma are analyzed every year.

  3. There has been a 2000% increase in rate of melanoma since the year 1930. One out of fifty get affected by this cancer.

  4. There has been a high rise in the rate of melanoma from 1970 to 2008. There has been an 800% increase in young women and 400% increase in case of similar aged men.

  5. Early recognition makes melanoma treatable. It is screened for growth very minimally.

Primary causes Melanoma may be caused primarily due to these causes:

The most primary cause of melanoma is ultraviolet light (UV) in people with a low level of skin pigment. The UV light might be from either the sun or from different sources, for example, tanning devices. Around 25% of cases occur from or in the form of moles.

The individuals who work on airplanes seem to have an expanded danger, due to more contact with UV rays.

Ultraviolet UV light of wavelengths between 315 - 280 nm from the sun react with the skin cell DNA and result in a kind of direct DNA harm called cyclobutane pyrimidine dimers (CPDs).

In order to stay away or avoid melanoma, you should:

  1. Avoid the sun at peak hours.

  2. Examine your skin at times for some kind of change.

  3. Keep away from tanning salons. Melanoma is a dangerous form of cancer and causes a lot of deaths. You should stay away from anything that causes melanoma. If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

4327 people found this helpful

Skin Cancer - Can Viagra Be The Cause?

MBBS, M.D Psychiatry , Diploma In Psychological Medicine
Sexologist, Navi Mumbai
Skin Cancer - Can Viagra Be The Cause?

Sildenafil (Viagra), whose function is to inhibit a substance called Phosphodiestarase-5 or PDE5 - was initially used only for the treatment of angina pectoris (a cardiovascular problem) and pulmonary hypertension. Incidentally, it was discovered that it could help the issue of erectile dysfunction too, and thus became hugely popular in the late 1990s. The little blue pill, as it was called, ruled more than 50% of the sexual dysfunction market for more than 15 years. However, as its popularity and usage increased, so did the scientific information about this drug, and now there is an increased speculation that it could be contributing to skin cancer, specifically melanoma. This is considered as one of the most dangerous forms of skin cancer and so the safety of Viagra sildenafil came into question.

Research has shown that users of Viagra sildenafil are at a higher risk for developing melanoma. There are reports stating that about 45 million men are at an increased risk of developing melanoma due to associated Viagra sildenafil use. The risk of developing melanoma was found to increase in men using ED drugs by 21%. Though there is no conclusive proof as yet that sildenafil is the cause, research is increasingly pointing out its role in melanoma. For example, PDE5 inhibitors (sildenafil, tadalafil, vardenafil) are known to promote melanin synthesis, which may exacerbate melanoma development.

The analysis of biochemical pathways of this correlation suggests that Viagra sildenafil triggers a special biochemical action involving the growth-stimulating cGMP (cyclic guanosine monophosphate (an intracellular signaling molecule) which in turn promotes the growth of malignant melanoma. In normal cases, the enzyme phosphodiesterase type 5 (PDE5) regulates the cGMP preventing any adverse cellular activity. Sildenafil inhibits the production of this enzyme, and potentiates a specific cGMP-related biochemical mechanism (called cGMP-cGKI pathway) , and thereby contributes to malignant melanoma. This has been proven to happen in mice and is yet to be proven in humans.

However, there are also reports which suggest that this does not happen due to Viagra sildenafil per se, but due to greater exposure to sun, which even otherwise increases the chances of skin cancer in general, and melanoma in particular. The countering theories also say that the population in which skin cancer was detected, comprised mostly of high income individuals who spent a significant amount of time holidaying on beaches and are not connected to the extensive use of Viagra per se. 

Therefore, though there is a correlation that has been established, there is no definite proof that Viagra sildenafil causes skin cancer. It is however, advisable to use ED drugs after medical consultation. If a patient has a genetic predisposition to develop melanoma, it is advisable to seek medical advice before the use of ED drugs. Occasional use should not be harmful. Also, when going out in the sun, limiting exposure to direct sun and UV protection should be managed too. If you wish to discuss about any specific problem, you can consult a Sexologist.

5198 people found this helpful

My mother is suffering. From ovarian cancer, stg 3 c and she is going to take chemo, low dose once a week for 3 weeks and after ultrasound, doctors will decide next step. The doctors have prescribed uidliv300, twice a day And moxif 400 once a day for 5 dayd. Now she is experiencing body pain, headache, head reeling, fever and vomiting. What to do. Are these side effects of the medicines? Pl help.

MD - Homeopathy, BHMS
Homeopath, Vadodara
They may not be side effects of the medicines but symptoms of the disease.. What I would like to suggest is give her homoeopathic medicine..(with proper consultation only) It may not cure her but will keep her more healthy and will allow to go through chemo as you know there are many side effects of chemo....

I am 70 years old male. What should be blood urea level in my body my s. Creatinine is 1. 4. My ultra sound exams for prostate reads post void 5 ml. Please advise.

PDDM, MHA, MBBS
General Physician, Nashik
I am 70 years old male. What should be blood urea level in my body my s. Creatinine is 1. 4. My ultra sound exams for...
In general, 7 to 20 mg/dl (2.5 to 7.1 mmol/l) is considered normal. But normal ranges may vary, depending on the reference range used by the lab, and your age.

I am 27. Every month I will get breast pain at least from 15days fron my childhood. But this time I do not have any pain and I did not period till now. I have gone through pregnancy test but it is -ve. What might b d prob.

MD - Obstetrtics & Gynaecology
Gynaecologist, Mumbai
If you have missed period by 7 days then only pregnancy test to be done. Pregnancy is one of the reason apart from hormonal changes, that you did not had same symptoms of breast pain this time.

MY daughter is having SOL in her Rt breast and she is 15 years of age. USG has been done but report is not given. But while doing usg sol appeared in the screen. What does it mean and is my daughter is going to have cancer type anything?

MBBS, M.S. General Surgery, M.R.C.S. England, M.Ch. Surgical Oncology, DNB Surgical Oncology, FEBS Surgical Oncology, DNB General Surgery, MNAMS, FMAS, FIAGES, FAIS, FICS, FEBS Breast Surgery, FACS, Fellowship IFHNOS & MSKCC USA, Fellowship in breast and oncplastic Surgery
Oncologist, Mumbai
It may be a fibroadenoma or a fibrocystic change. Cancer is quite rare at this age. Better to see a breast surgeon who will examine her clinically if not already done. Also wait for the ultrasound report. Feel free to contact me directly if you want to discuss this further.

My question for all doctors what's region of blood cancers? And what's treatment of blood cancers. Because my small bro have blood cancer.

DNB, MBBS
Oncologist, Faridabad
There is no specific cause of blood cancer it could be due to genetic factors, exposure to radiation, or some other environment factors but nothing is very specific. It is treated by chemotherapy for prolonged period. Good luck to your brother now a days complete remission is possible with complete treatment.

Is lungs cancer and blood cancer communicable? Are they transform when food and water is shared with cancerous patient.

DNB, MBBS
Oncologist, Faridabad
No sir, cancer is not a communicable disease, it's absolutely safe to share food and water, though we like to advise adequate hygiene for cancer patients as they are immunocompromised and likely to catch infections fast, so one should not share food, but this is to prevent infection, not for prevention of cancer spread.
14 people found this helpful
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