Doctor in Indira IVF - Bhubaneswar
Patient Review Highlights
What is In- Vitro Fertilization?
In Vitro fertilization (IVF) is a process of fertilization where an egg is combined with sperm outside the body, in vitro ("in glass"). This process involves stimulating a woman's ovulatory process, removing an ovum or ova from the woman's ovaries and fertilizing them with sperms in a liquid in the laboratory. The fertilized egg (zygote) undergoes embryo culture for 2–6 days, and is then transferred to the same or another woman's uterus, to establish a successful pregnancy.The success rate depends on various factors such as maternal age.
Cause of infertility
- Embryo status
- Reproductive history
- Lifestyle factors
Ways to increase the success rate of In-Vitro Fertilization:
- Maternal age: Young age females undergoing IVF are more likely to get pregnant with a donor egg as compared to women older than 41yrs of age. If a woman undergoes IVF treatment by 23–39 years of age, the success rate is higher.
- Reproductive history: Women who have been previously pregnant have higher chances of being successful with IVF treatments than those who have never been pregnant.
- Avoid tobacco smoking: As it reduces the chances of IVF producing a live birth by 34% and increases the risk of an IVF pregnancy miscarrying by 30%.
- Maintain Body mass index (BMI) between 20-27: A body mass index over 27 causes a 33% decrease in likelihood to have a live birth after the first cycle of IVF.
- Avoid obesity: Pregnant women who are obese have higher rates of miscarriage, gestational diabetes, hypertension, thromboembolism and problems during delivery. Obesity in pregnancy may also lead to an increased risk of fetal congenital abnormality.
- Reduce alcohol and caffeine intake: As increased alcohol/caffeine intake decreases success rate of IVF.
- Number of embryos: Increasing the number of embryos transferred in the treatment cycle increases the success rate of conceiving.
- Getting treated for illnesses before IVF: Taking proper treatment for the underlying autoimmune disease before starting with IVF treatment is essential as it plays a role in decreasing IVF success rates by interfering with proper implantation of the embryo after transfer.
- Treating infectious disease: If the female undergoing IVF is suffering from any infectious disease like Rubella, Toxoplasmosis, etc needs to take treatment for the same as it may increase the failure rate of IVF by causing miscarriage/abortion or it may cause failure to hold the fetus.
- Mental state: The mental state of the female while undergoing IVF plays an important role. Females undergoing any kind of stress either physical or mental have higher chances of failure.
- Good clinic: Getting IVF treatment done from a good clinic and experienced doctor helps in achieving success.
In case you have a concern or query you can always consult an expert & get answers to your questions!
Not being able to get pregnant can be an agonizing experience. The fertility of an individual can be affected by a host of physical and mental factors. The effectiveness of a fertility treatment is enhanced by several folds if there is an accurate diagnosis of the underlying cause of infertility. The In Vitro Fertilization (IVF) that first made its presence felt in 1978 (the first child born through IVF was on 25 July 1978) has been a revolution and is still continuing to change lives of millions of couples dealing with infertility issues.
When we talk about IVF, a question that often comes to our mind is whether IVF is the solution to all infertility problems? To answer this question, one needs to have a proper understanding of the IVF procedure. The
IVF procedure essentially comprises of following things:
- Stimulation of the ovary and development of the follicles involves a series of tests and ultrasounds to closely monitor the ovulation process, including the quality and quantity of eggs released along with the hormonal balance.
- In some instances, medications or hormones may be needed to ensure that the ovaries are stimulated enough to ensure proper development of the follicles (sacs filled with fluids where maturation of eggs take place) along with the release of two or more eggs during each cycle.
- Retrieval of the eggs: This step involves isolation of the eggs or the oocyte from the follicular fluid into a culture media and finally into an incubator.
- Fertilization: With the retrieval of the eggs, the sperm samples (from the partner or a donor) are also collected to facilitate the fertilization process (the chosen active sperm may be injected into the egg or mixed with it).
- Transfer of the embryo: From the embryos resulting from fertilization, a doctor selects the healthiest one and transfer it into the uterus of the recipient woman for implantation to take place.
- Following the implantation of the embryo, many women get pregnant within a few days or weeks. However, a pregnancy test can also result in disappointment for some.The failure of IVF treatment in some patients can be attributed to
- The embryo not being healthy enough to undergo the implantation
- Problems or severe damages to the uterine cavity.
- Abnormalities with the egg or the sperm (can be chromosomal or genetic aberrations).
Can IVF solve all infertility problems?
Having a clearer understanding of the IVF procedure, one can state that IVF does come as a ray of hope, especially for
- Males with a low sperm count
- Tubal damage in women. There may also be problems affecting the cervix and the vagina
- Women with ovulation problems (can be due to Hormonal Imbalance, PCOS, Endometriosis) or those who are above 35 years
In unfortunate cases, where IVF fails to produce the desired result, there are other fertility treatments available such as Intrauterine insemination, Gamete or Zygote Intrafallopian Transfer, Intracytoplasmic sperm injections, to put an end to the infertility problems.
In case you have a concern or query you can always consult an expert & get answers to your questions!
In vitro ova) from a woman's ovary are removed. They are combined with sperm outside the body in a laboratory procedure, and then the fertilized egg (zygote) is transferred to the same or another woman’s uterus for a successful Infertility
- Blocked fallopian tubes
- Women with ovulation disorder
- low sperm count or poor quality sperm
- Genetic disorder
Two procedures are done to gain access to ovaries
- It involves inserting the needle through the vagina (transvaginally). With the help of an laparoscopy, a small thin tube with a viewing lens is inserted through an incision in the navel. This lets physician to see inside the patient, and locate the ovaries.
Without additional techniques, the chances of pregnancy would be extremely small. The additional techniques used in IVF include-
- Ovarian hyperstimulation- Stimulation to induce development of multiple follicles of the ovaries.
- Final maturation induction- Induction of final oocyte maturation is performed, generally by an injection of human HCG), when the ovarian follicles have reached a certain degree of development. This is known as the "trigger shot”
- Egg and sperm preparation- Semen is prepared for fertilization by removing inactive cells and seminal fluid in a process called sperm washing. An oocyte selection may be performed prior to fertilization to select eggs with optimal chances of successful pregnancy.
- Co-incubation- Eggs are removed from the woman and placed in one of the fallopian tubes, along with the man's sperm. This allows fertilization to take place inside the woman's body. Therefore, this variation is actually an in vivo fertilization, not in vitro.
- Embryo culture- The main durations of embryo culture are until cleavage stage (day two to four after co-incubation) or the blastocyst stage (day five or six after co-incubation)
- Embryo Ectopic pregnancy
- Ovarian rupture, anesthesia
Having a baby is a life changing event. For every couple the process is different. For some getting pregnant happens naturally but for others the whole process of getting pregnant can become an ordeal. For couples experiencing difficulty in getting pregnant, there is IVF (in vitro fertilization) fertility. It should be stressed that IVF is one of the many ways in which a couple can have a child.
The women are generally the one undergoing the treatment. The husband’s male ego maybe hit owing to the fact that he is unable to produce a baby through natural process. The problem of infertility may be traced back to the husband or the wife or both. In an IVF treatment, the woman is generally injected with hormonal medications and the egg is extracted and then fertilized with a sperm and the resulting embryo is implanted in the womb. The whole process might be overwhelming for the woman. The husband basically plays a passive role but is pivotal in providing support and love to his better half.
What can husbands do during an IVF treatment?
- Appreciation- The decision of having a baby is an important one. However, getting pregnant through IVF can take a toll on the woman with mood swings and low self-esteem. In such situations, the husband needs to play the supporting role and appreciate and praise her for doing such an incredible task. If she is feeling down, cheer her up and do not criticize. Pamper and appreciate her.
- Providing Emotional and Physical support- Women are generally emotional by nature and the process of IVF can make them more emotional. A woman can experience fatigue and nausea during the process. The husband should be around to help his wife in doing household chores and any other activities she needs help in doing. Remember a simple hug or just holding hands can create a positive feeling in your partner. You should spend time together
- Research- The women bears the maximum burden, being the one to go through the IVF treatment, experiencing pain and giving birth and taking care of the baby post-delivery. A husband can relieve some stress by undertaking a thorough research on IVF fertility. It’s very important to discuss about the consequences as well, like what measures can be adopted if the treatment is unsuccessful.
The whole process IVF might seem difficult and expensive but with the support of the right doctors and your partner, you will soon get to experience parenthood and an overwhelming love for your baby. In case you have a concern or query you can always consult an expert & get answers to your questions!
Getting pregnant can become an immensely frustrating experience for women with endometriosis or cyst with IVF treatment. Many women with endometriosis worry about whether they will be able to conceive and bear a child. This is because, in such a case, there is a collection of endometrial tissues outside the uterus that results in a painful inflammation along with the formation of blood-filled cysts in the ovary and bands of scar tissues.
How does PCOS or endometriosis affect the process of reproduction?
When a woman has any of these fertility issues, there could be endometrial growths of the tissue hindering the normal functioning of the reproductive organs. When the endometrial tissue formation involves the ovaries, there is a restriction on the release of eggs. On the other hand, when the fallopian tubes are affected, it would prevent the sperm from reaching the egg or it may also stop the fertilized egg from travelling to the uterus. Though each of these instances may sound challenging, experts suggest that IVF treatment can be helpful in offering desired results. It is estimated that about one-third of women suffering from endometriosis can conceive naturally without any treatment whatsoever. But for the rest of the women that suffer from endometriosis, IVF can be the best bet.
How can IVF help in getting pregnant in this scenario?
In order to make pregnancy possible for women with multiple adhesions, endometriosis or PCOS, the doctor would definitely begin with a comprehensive evaluation of hormones along with the presence of other chemicals in the body. Diagnostic tests such as hysteroscopy, hysterosalpingography, and laparoscopy can also be of great value in offering an insight into the individual patient’s condition.
When the IVF process has been successful, the embryo will get implanted in the uterus and cause the much-desired pregnancy. If there is any embryo remaining, it may be stored for use in future or donated to other couples. IVF is deemed successful for overcoming most of the female factor caused infertility including cyst, PCOS, and even endometriosis. There are 5 fundamental steps in IVF and they are:
- Super-ovulation or the process of stimulating the reproductive organs of a woman for releasing numerous healthy eggs. This is the first point of contradiction between IVF and normal pregnancy where a single egg is released and ovulated.
- The second step constitutes retrieval of eggs and sperm collection
- Then there is insemination as well as fertilization of the eggs with the help of the sperm
- Development of embryos and subsequent genetic evaluation when needed
- Transfer of the embryo in the uterus of the woman
Since IVF allows a controlled interaction between the egg and the sperm, it offers a high rate of success even when the patient is affected by complex disorders such as endometriosis, PCOS or cyst. Hence, discuss with your doctor if it is a viable option for the given situation. In case you have a concern or query you can always consult an expert & get answers to your questions!
IVF refers to In Vitro Fertilization, which is an assisted reproductive technology, is one of the most effective and popular treatment options for people facing fertility issues. When the initial or basic IVF treatment fails, additional advanced treatment options become necessary in order to make the IVF procedure successful. Read on to know more about the different treatment options available in IVF in detail.
- ICSI: ICSI or Intra-cytoplasmic Sperm Injection is a specialized form of in vitro fertilization. This treatment is required when the sperm is found to be abnormal. The procedure is the same as that of basic IVF and is performed in the laboratory where ICSI sperm injection is given to the female egg in order to fertilize it.
- Blastocyst: In normal IVF procedure, after the egg collection, the embryo is transferred inside the utterers usually on day two or day three. But, there is also an option to let the embryo grow further till day five when the blastocyst is formed and is then transferred inside the uterus, as per the requirement of the patient’s situation.
- PGS/PGD: The term PGD refers to Pre-implantation Genetic Diagnosis whereas PGS refers to Pre-implantation Genetic Screening. Just as the names suggest, both these treatments are performed by collecting single cells from the newly formed embryo and are then diagnosed and screened for the presence of specific genetic conditions for checking of the normalcy of the chromosomes of the embryo, before transplanting the embryo inside the uterus.
- Laser-Assisted Hatching: Laser-assisted hatching becomes essential in case the embryos fail to hatch themselves in the interior wall of the uterus (uterine wall). This treatment intends to help during the hatching of the embryo from its protective shell in the outer section while promoting implantation once the embryo is transferred inside the uterus.
- Frozen Embryo Transfer/FET: FET or Frozen Embryo Transfer refers to a cycle where the frozen embryos are used for establishing a pregnancy. Here, the embryos from the previous egg cycle or IVF are frozen and then transferred back into the uterus of the female in case the previous embryo transplant fails.
Both PESA or Percutaneous Epididymal Sperm Aspiration and TESA or Testicular Sperm Aspiration are both minor surgical procedures that are performed for finding sperm when the male partner is found to be suffering from Azoospermia which is the absence of sperm when he ejaculates.
Depending on the fertility condition of the patients, previous response to the IVF treatments, and the result of the previous IVF treatment, the IVF treatment options one has to go through may vary. You must consult with your IVF specialist to know whether and which of the advanced IVF treatment options you may have to opt for to ensure a healthy pregnancy as well as a healthy baby.
What is HIV?
The human immunodeficiency virus (HIV) is a kind of lentivirus that causes HIV infection, and over time it causes acquired immunodeficiency syndrome (AIDS). Acquired immunodeficiency syndrome causes progressive failure of the immune system leading to life-threatening opportunistic infections and cancers to thrive. A study by anonymous questionnaire in over 900 HIV-positive people using combination therapy (80% men, 20% women) found that around one-third reported less interest in sex.
Effect of HIV on Sex Life
- People find that their sexual desire or performance is affected when they are first diagnosed as HIV positive.
- A person is worried about the impact of the diagnosis on the current relationship(s) and also on chances of creating new ones, especially with someone who is HIV negative.
- Some people may experience lack of pleasure while having sex as they may have to use a condom to avoid transmission of the virus.
- Lower (than normal) testosterone levels have been found in people with advanced HIV infection leading to sexual dysfunction.
- Untreated HIV can also cause nerve damage (a condition called neuropathy) resulting in erectile problems.
- Women with HIV may experience menopause (the end of your menstrual cycle) earlier than women who are HIV negative due to abnormal production of the female hormones estrogen and progesterone. Fall in the level of these hormones causes a reduction in sexual desire.
- Experiences such as receiving a positive HIV test result are likely to be a time of shock, worry, fear, or disbelief because of which sexual desire and performance can be affected.
- Concerns about possibly passing HIV on to sexual partners can also affect your desire for sex and intimacy.
- Anti-HIV drugs, such as the ddI (didanosine, Videx/Videx EC), may cause numbness in the genital area, causing difficulty in obtaining or sustaining an erection.
- In relationships, the diagnosis of HIV may reveal aspects of a person's behavior that they may have wanted to keep private. This may include infidelity or sexuality (such as male homosexuality) or intravenous drug use resulting in feelings of guilt and blame.
- Some individuals keep complete abstinence from sexual activity due to the myths and beliefs heard from people in their surroundings. This leads to unhappy relationship between spouses.
Both women and men gave similar reasons for having not resumed sex, and these were:
- Not having recovered fully
- Insufficient energy
- Lack of privacy as they shared a sleeping house with children
- Lost interest in sex
- Followed the health workers advice of not engaging in sex
- Fear of superinfection
- Fear that the virus would regain strength
- Sex no longer was an important part of their lives
In case you have a concern or query you can always consult an expert & get answers to your questions!
IVF or In-vitro fertilization is a procedure in which a woman’s egg is taken out of her body and infused with the sperm in a medical laboratory. This is an artificial method of fertilization, which can help people overcome a range of issues stopping them from becoming biological parents to their child. However, as is the case with many modern medical procedures, there exist several misconceptions about IVF and what it does.
Here is a look at some of the myths concerning IVF, which you definitely should not believe.
- IVF is the only option for infertility: This is a misconception among the populace. If you or your partner is diagnosed with a fertility issue, your doctor will suggest many other treatment options prior to suggesting IVF. In-vitro fertilization is used when all other treatment options have failed to produce the desired result or pregnancy. For instance, infertility in women can be caused due to the formation of cysts in the uterus. A simple surgery to remove such cysts may be enough to cure infertility, therefore not needing IVF for pregnancy.
- Insurance covers IVF treatment: Most health insurance does cover the cost of treatment for infertility. However, the IVF procedure is rarely covered by any such insurance. This is because the treatment involves considerable cost that most insurance companies do not want to deal with. So, before signing on to a health insurance, ensure that you and your partner are aware of the treatments covered by the same policy.
- IVF raises chances of having twins or triplets: There is some truth to this myth. During the initial In-vitro fertilization cases, doctors often fertilized two eggs at once and fused them into the mother. This was done because the success rate for such a procedure was lower and doctors hoped that fertilizing two eggs at once would increase the chances of pregnancy. However, modern medicine has advanced quite a bit since then. This has led to clinics implanting only one fertilized egg in the mother, leading to the birth of just one child.
- IVF babies are at greater risk for birth defects: Another misconception that may harbour is that babies born through IVF are rarely healthy. However, this is not true. Birth defects in IVF babies occur at the same frequency as they do for babies born through the natural process. So, people should stop worrying about their children suffering from chronic diseases, just because their mothers have undergone the IVF procedure.
Pregnancy can be easy and smooth, while on the other hand, it might be time consuming, marred with conception difficulties all along the way. Pregnancy may seem exciting to some, whereas it can be stressful for others. Regardless of whether it is the first child you are planning or have had a successful pregnancy previously; there are some tips you need to keep in mind in order to improve fertility and give birth to a healthy child.
Some fertility boosting factors are:
These fantastic swimmers are at the very root of male fertility. Some important components which need to be taken into consideration are sperm count, sperm motility (the ability of the sperm to swim around the female reproductive tract) and morphology (shape and size of a sperm). In order to have all these parameters in check and working fine, one needs to abstain from smoking and limit alcohol consumption among many other lifestyle modifications.
Having unprotected vaginal intercourse during the woman’s fertile days in a month helps improve chances of conception.
Fertility becomes a challenge when you are either overweight or underweight. The weight of a woman affects ovulation (The release of eggs from the ovaries) and causes hormonal imbalance; factors which make it very difficult to conceive. Keep your weight levels in check and that could prove primarily essential in bettering your fertility.
Staying well nourished boosts your odds of conceiving! Make sure to include enough protein, iron, zinc, vitamin C, and vitamin D in your diet, because deficiencies in these nutrients have been linked to lengthened menstrual cycles (and therefore less frequent ovulation) and a higher risk of early miscarriage. Ask your gynaecologist if you should take a daily multivitamin supplement. And be sure to eat protein-rich foods, such as meat, fish, low-fat dairy products, eggs, and beans.
Beware of STDs or Sexually Transmitted Diseases. One is the most prone to STDs of any kind if he/she happens to engage in unprotected sexual intercourse; having a number of sexual partners just ups the chances of getting afflicted by STD. Protected vaginal intercourse helps prevent STDs, thus enhancing fertility and subsequently, chances of conception.
According to several studies, the lubricant one chooses surprisingly plays a significant role in determining fertility. Not all lubricants boost fertility and sperm motility (sperm count). Baby oil or egg whites are a few good examples of such lubricants.
While a limited amount of caffeine consumption is good, overdoing it might spoil and hamper fertility. Limit caffeine intake and keep it within a level of 200-250mg a day.
Smoking, besides playing havoc with every organ in the body, affects the reproductive organs and thus fertility. In men, it leads to reduced sperm count and in women, it causes DNA damage. Stub the bud right now and never get back to it.
Certain toxic chemicals can lead to female and male infertility. So it is advisable that you stay away from chemicals such as pesticides, organic solvents and lead, the primary toxins which pose a severe threat to fertility.
- Exercising regularly can never go wrong. It gives you the strength and stamina, boosting your overall health. However, vigorous exercises, especially when you are trying to conceive, will do you no good. It might adversely lead to the suppression of certain hormones such as progesterone (pregnancy stimulating hormone) and might affect ovulation, hence affecting fertility. Aim at a regular 20 minutes session of light exercises; mild cardiovascular exercises such as walking can work wonders, especially in such circumstances.
IVF procedure is often used for surrogacy. Surrogacy is a process where a healthy woman’s womb is used for the proper development of the fetus from the time of fertilization till the time of birth. Surrogacy is divided into two parts, namely, traditional surrogacy and gestational surrogacy.
Traditional surrogacy is the process where the sperm of the father is introduced into the egg of the surrogate mother for the pregnancy. In such a case, the surrogate mother is also the biological mother of the resulting child. Gestational surrogacy is a process where a fertilized egg is introduced inside the surrogate mother. In such a surrogacy, the surrogate mother’s genes are not passed onto the child.
Gestational surrogacy is quite beneficial for the surrogate mother and can be the ideal choice for many. Here are a few of the advantages of gestational surrogacy.
- Reduction of risk of breast cancer and ovarian cancer: Most people do not know that being a gestational surrogate mother can reduce your risk of developing breast and ovarian cancer. This is because during the pregnancy, the body’s hormone levels spike quite substantially. These hormones also protect your body against cancer. Research has revealed that gestational surrogacy is the most effective against breast and ovarian cancer and may even help to reduce chances of other cancers.
- Improves heart muscles: A gestational surrogate mother has a lot of other benefits as well. One such benefit is the improvement of the cardiac muscles. The real reason for this change is not known, but researchers feel that any hormonal change during the pregnancy can be a cause. The improved functioning of the heart can be quite effective during a second pregnancy for the same mother.
- No healthcare costs: The intended parents of the surrogate child are liable to pay all the healthcare bills of the surrogate mother throughout the duration of the pregnancy. This means that the gestational surrogate mother does not have to worry about spending money in a bid to treat any adverse side effect of the pregnancy. Since the child will go to the intended parents after birth, they are liable to pay for all the medical costs.
However, no surrogate mother chooses surrogacy in order to receive these benefits. Instead, they opt for the procedure in a bid to do some good for the society and let the intended parents feel the joy of having children.