Loeys-Dietz Syndrome is a disorder that affects the connective tissues in many parts of the body. These connective tissues provide strength and flexibility to the body structures such as bones, muscles, ligaments and blood vessels. There are four types of Loeys-Dietz Syndrome (which are named as I to IV). All of the types show similar symptoms that may be present in childhood or adulthood. The most prominent symptom is enlargement of aorta, the blood vessel that carries blood from heart to the rest of the body. People with Loeys-Dietz Syndrome may have abnormal skeletal problems like premature fusion of the skull bones, abnormal curvature of the spine, sunken or protruded chest, flat feet, elongated limbs or inward or upward turning feet.
HOW IS LOEYS-DIETZ SYNDROME DIAGNOSED?
The general physician will evaluate you physically and recommend genetic testing. Early diagnosis is important to prevent the rupture of aorta and other heart complications.
HOW IS LOEYS-DIETZ SYNDROME TREATED?
Medications to relieve pressure on the aorta, such as angiotensin receptor blockers can be prescribed to patients. Vascular surgery for arterial repairs to prevent aneurysms can be advised.
DID YOU KNOW?
However, these children are rarely able to continue with normal lives and usually have a shorter life span too. They have to refrain from playing most sports too.