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The most commonly encountered two facts about the drug or alcohol use by our addicted kids are drugs/ alcohol are something which they really like those are something which they find really hard to give up. They know that the drug can kill them in a long run, but still they go with the immediate rewards by consuming the drug. The whole addiction thing is about being in the moment and choosing what your brain craves for right now at the expense of other rewards and possibilities. So what we observe is that drug hijacks a person's rational thinking for the long term consequences.
Addiction has to do with changes in the brain that come about gradually, become more and more central, more and more powerful as the time passes by. The drug use becomes the axis of the person, around which the other activities in life takes turn. It takes on the central meaning and role in the person's life in such a way that the most irrational idea about taking the drug or alcohol may seem to the person the most rational in that particular situation, as the drug compromises the person's clear thinking. So yes an addict can make choices for his drug cravings but the way they make choices is the thing we must think about. In an addict the brain does what it needs to do, but in a very non-adaptive way. In simple words addiction hijacks the very parts of the brain that are supposed to fix it.
Craving is the fundamental psychological experience of an addict because of which addiction occurs. Dopamine serves as the fuel for craving and is the common pathway for all kinds of addictions. Natural goodies like the food and sex certainly release dopamine in brain and follow the progression from liking to wanting i. E. Wanting more of those. As per studies, among the natural rewards sex can provide a person with the maximum natural high of upto 200% dopamine levels in brain. But the drugs cause a higher than 200% dopamine levels, which thus is the magic mark for addictive processes to occur. Also with repeated drug use there are changes in the arrangement of the inner landscape of synaptic architecture in brain, such that the thoughts, the images, the memories about the drug use behavior takes over many parts of the cortex of brain and thus the person see the drug cues wherever he gets a dopamine rush, be it with sex or food or social gatherings. Thus dopamine drives the person with a feeling of craving for the drug. Also with repeated dopamine increments of higher than natural amounts, there is maladaptive learning in brain in form of the shrinkage of dopamine cells, decrease in dopamine receptors and depletion of the dopamine stores. Thus the real natural goodies like sex or food are than not able to give a dopamine high and the only way left is to have more drugs. The person becomes impulsive and compulsive in his drug taking behavior. Repetition compulsion feedback loop keeps the person going after the drug use, narrowing the sense of meaningful world for the person. This causes a vicious cycle of incremental drug intake and thus addiction. Dopamine pathways are subdued by chronic drug use and thus the drug addicts are never able to keep up with their promises of staying away from the drug.
But then our brains have enormous reparative capacity and so a lot of the things that drugs do to damage the brain are probably reversible. One of the things that last the longest are the memories associated with drug use and the learning/ operant conditioning that occurs with it. The acute memory of brain over stimulation with drug is captured in amygdale which designates an important part of the instinctual brain i. E. The brain part which can't be controlled. So if a drug related cue is presented to a recovering addict, all that they can remember is the greatest high which they ever had with the drug. Thus the person remains preoccupied and thinks about the drug even when not using it. When this occurs, it is for the lifetime and we can't undo it. Their amygdale are going to light up seeing the drug cues for rest of their lives. This is why we say recovery from drug is a lifelong experience. Studies show a much faster depletion of our brain neurotransmitters by drug use (less than 12 months), than their replenishment in recovery from addiction (5 to 7 years). Thus during recovery an ongoing treatment for the imbalanced brain neurotransmitters and the visible symptoms due to the same is always essential.
I am a 56 yr old male. I have constant heartburn unless I take zantac. Switched to prilosic then priolosic generic without magnesium all solved my heartburn. I have constant diarrhea esp. After going out to eat. My stomach constantly makes noises, is bloated & I have a lot of gas. I am lactose intolerant & stay away from milk & dairy which is hard since is included everywhere. My constant diarrhea is sometimes a heavy liquid stream of fices. Other times it is very soft stool. I am uninsured & cost is a problem so I haven't been to a Dr. Please help if you need more info contact me. Thank you.
I am 55 years old male. I am free from diabatic melitus. I fee little numbness in my left hand fingers and and left foot for the past 5 years. I have undergone 2d echo, treadmill test and angiogam in jan-15 and it is normal, but my cardiologists adviced me to take tonact tg (statins) fopr profilactic measure. I am contnuing the medicine. I regularly paly shuttle and fit to play. On and off this numbness is nagging me and laeding some suspect in my health. Also vitamin d, nerve conduction and spine x ray revealed no abnormality. I have acid related symptoms when food deviated from normal food. Please advise.
I developed a leg sprain when I got into the bus as the driver took it off as soon as I kept my foot on the first step. Now I can't climb down the stairs without pain [right leg alone]. Left is alright. Could you help me, please? I am 54 years old woman.
Hi sir my name is Ravi working in bank suffering from pharyngitis from the past one and half year I consulted 3 specialists also. During taking medicine no problem when medicine stopped daily while eating when anything eating touches throat tears come from eyes and sneezeAt night time severe cough at midnight please suggest some remedies.
Hello doctor, I am 25 year old. My question is, since frm an year I hav an unprotected sex wit my girlfriend whose age is also 25. I believe it's an 1st sex for both of us. This ws continued for 5 times without any condom nor protection. I just want to ask is der any possible of getting any problems/HIV fr both of us? Is it compulsory to hav safe sex every time? I wil b waiting for your response fr my question.
Diabetes is a disorder that is characterized by an inability of the pancreas to produce enough insulin or effectively utilize the insulin produced by the body. Insulin is the hormone that is produced by the pancreas to metabolize sugar in the body, the sugar that is present in the food that you consume.
Diabetes is commonly classified into two types: Type 1 and Type 2 diabetes.
In Type 1 diabetes, the cells in the pancreas do not produce insulin in the required amounts; this disorder usually tends to occur in children. Type 2 diabetes generally occurs in people who are above 40 years of age; this type is characterized by an inability of the body to efficiently utilize the insulin produced by the pancreas.
How can diabetes affect your kidneys?
Too much glucose, also called sugar, in your blood from diabetes damages your kidneys’ filters. If the filters are damaged, a protein called albumin, which you need to stay healthy, leaks out of your blood and into your urine. Damaged kidneys do not do a good job of filtering wastes and extra fluid from your blood. The wastes and extra fluid build up in your blood and make you sick.
Diabetes is a leading cause of kidney disease. Diabetic kidney disease is the medical term for kidney disease caused by diabetes. Diabetic kidney disease affects both kidneys at the same time.
Signs of Kidney Disease in Patients with Diabetes
- Albumin/protein in the urine
- High blood pressure
- Ankle and leg swelling, leg cramps
- Going to the bathroom more often at night
- High levels of BUN and creatinine in blood
- Less need for insulin or antidiabetic medications
- Morning sickness, nausea and vomiting
- Weakness, paleness and anemia
What are the possible complications?
- End-stage kidney failure: If this occurs then you would need kidney dialysis or a kidney transplant.
- Cardiovascular diseases: Diabetics have an increased risk of developing cardiovascular diseases, such as heart disease, stroke and peripheral arterial disease. If you have diabetes and diabetic kidney disease, your risk of developing cardiovascular diseases is increased further.
- High blood pressure: Kidney disease has a tendency to increase blood pressure. In addition, increased blood pressure has a tendency to make kidney disease worse. Treatment of high blood pressure is one of the main treatments of diabetic kidney disease.
What to do?
- It is essential to get your urine checked at least once every year to detect signs of kidney damage.
- Some other symptoms that you may experience are swelling in the ankles, weight gain and a rise in your blood pressure.
- The first step to treat kidney damage caused by diabetes is to get your blood sugar levels under control.
- You should also avoid consuming medications that can cause damage to the kidneys.
- A kidney transplant or dialysis may be advised if the damage to kidneys is significant. If you wish to discuss about any specific problem, you can consult a nephrologist.