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Treatment of Kidney Stones
Treatment of Blood in Urine
Treatment of Kidney Disease
Treatment of Frequent Urination Problems
Kidney Dialysis Treatment
Treatment of Fluid Retention
Kidney Stones Treatment
Treatment of Kidney Transplant
Treatment of Kidney Failure
Treatment of Kidney Diseases
Treatment of Nephrotic Syndrome
Kidney Transplant Treatment
Treatment of TB in Kidney
Treatment of Nephropathy
Treatment of Nephrolithiasis
Treatment of Nephronophthisis
Treatment of Bartter Syndrome
Treatment of Renal Agenesis
Treatment of Alport Syndrome
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I found the answers provided by the Dr. Mahendra Mulani to be very helpful, knowledgeable, thorough, sensible and practical. Thanks a bunch
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I found the answers provided by the Dr. Mahendra Mulani to be knowledgeable. Information is useful for all.
Dr Mahendra Mulani's diagnostic accuracy and treatment protocols were re upto the mark
Sir Nature is Good....We were meet at shivalik hospital.
Very Good Doctor and his co-operation and nice behaviour
I get recovery in short time, best doctor
Alport Syndrome, first detected by Dr. A. Cecil Alport and named after him is a rare inherited disease. It affects the kidney and also the inner cochlea or ear and the eyes. Passed down through families, it is caused by genetic mutations that affect the type IV collagen family of proteins. Collagen is an important tissue that forms the basement structure of the kidney, inner ear and eye.
Types of Alport syndrome
X-Linked Alport Syndrome: A most common form of Alport Syndrome, boys who are affected with this type tend to develop serious complications and kidney failure.
Autosomal recessive Alport syndrome (ARAS): When both the parents carry the abnormal gene and pass it down to their offspring, this type of syndrome is caused. If affects the male and female with equal severity.
Autosomal dominant Alport syndrome (ADAS): This happens when the child inherits the abnormal gene from one of the parents. Only one copy is needed to cause a mutation.
Signs and symptoms of Alport syndrome
With all types of Alport Syndrome, the tiny blood vessels of the kidney called glomeruli are damaged and the kidney will be unable to filter the toxins from the body. The most common symptoms include:
- Hematuria – Blood in the urine
- Proteinuria – Protein in the urine
- High blood pressure
- Edema – Swelling in the legs, ankle, feet and around the eyes
- Hearing and vision problems
- Flank pain
The following tests and examinations can be performed to assess the condition and type of Alport Syndrome:
1. Urine test – It helps in finding the presence of blood or protein in your urine
2. Glomerular Filtration Rate – The blood work assesses the levels of waste and protein in your blood
3. Kidney Biopsy – A tiny piece of kidney is removed with special needle and analyzed
4. Hearing Test – It checks, if hearing is affected
5. Vision Test – This is conducted to check any abnormalities in vision
6. Genetic Test – It determines the type of Alport syndrome and confirm the diagnosis
There is no specific treatment for Alport Syndrome. However, treatment aims to relieve the symptoms and slow the progression of kidney disease.
- Medications to control high blood pressure
- Diuretics or water pills
- Limiting salt or sodium intake in your diet
- Kidney transplantation if patient is progressing towards kidney failure
- Medications to slow down the onset of kidney damage
Awareness of family history of this disorder will help in detecting Alport Syndrome at an early stage and also help you take the right steps to prevent any further complications. Seek medical attention and contact a nephrologist immediately if you have a family history of this disease.
My protein creatinine ratio is 3.5gm.i know this from 24 hr PCR urine test. My doctor says my kidney will failure within 2to5 years. Really should I worry?
He is suffering from ckd. Creatinine is 5.2. It was detected a year ago. Dr. in chennai after seeing the reports said for dialysis or transplant. We came back to kolkata and visited for homeopathy treatment. At one point his creatinine was 3.7. Then fluctuated to 4 .now its static to 5. Is it dangerous. What should we do. Please help.
Kidney Angiomyolipoma is also known as AML of the kidney, renal angiomyolipoma or kidney AML. This is a benign tumor that can lead to hemorrhagic complications. A tumour can crop up in the medulla or the cortex of the kidney. A small proportion of this condition can happen in conjunction with tuberous sclerosis. The symptoms vary according to the size of a tumour. The treatment differs from case to case, for some patients, radical nephrectomy may work while for some, invasive wedge resection and partial nephrectomy may work better. The prognosis of this condition is excellent owing to its benign nature.
How is kidney angiomyolipoma medically dealt with?
The treatment option depends on the criticality of a tumour and the general health of the patient. A vast majority of the tumors that are asymptomatic in nature doesn’t require a surgical intervention. After the diagnosis is made, a doctor might want to take the wait and watch approach. If the tumor size is small, only medications can cure the condition. On the other hand, surgical intervention can cure the disease and limit any chances of recurrence. Some of the preferred surgical methods include complete or partial nephrectomy, endoscopic surgery, nephron-sparing surgery and tumor embolization. A nephrectomy is only considered when the tumor size is quite large. In case the kidney function is severely impaired, dialysis is necessary. If the tumor results in abdominal bleeding, emergency surgery should be considered.
Healthy lifestyle changes:
If a person has been diagnosed with kidney angiomyolipoma, it is important to follow a healthy lifestyle. Refraining from salt, potassium is a must. A stressed kidney, in general, is better off without foods such as potato, salt, fast food, processed food, various kind of meat etc. The dietary restriction gets waived off by the doctor once the patient is cured. Lifting heavy weight is a strict no in these circumstances. Adequate rest and enough hydration are necessary to be in shape. Timely consumption of medicine is equally important to get cured.
How can this disease be prevented?
Medical research has not fetched any result over the possible prevention method of renal AML. This condition is often connected with a genetic disorder. The following prevention method is necessary to mitigate the risk of this disease.
- A genetic test of the expecting parents or molecular testing of the fetus can help a doctor understand whether there is a risk involving the baby.
- If the disease runs in the family, a genetic counselling can help parents to understand to assess the risk before planning a child.
- Frequent medical checkups are also necessary for a person who has a family history of this disease.
- Aggressive medical research is being done to get a possible cure for this problem. If you wish to discuss about any specific problem, you can consult a Nephrologist.