Sideroblastic Anemia is a heterogeneous group of blood disorders characterized by an impaired ability of the bone marrow to produce normal red blood cells. Sideroblastic Anemia is classified as hereditary, acquired and reversible. The symptoms of Sideroblastic Anemia consist of fatigue, weakness, palpitations, and shortness of breath, headaches, irritability and chest pain.
HOW IS SIDEROBLASTIC ANEMIA DIAGNOSED?
The hematologist will go through the medical history of the patient and conduct physical examination. Various other laboratory and bone marrow examinations are recommended such as blood smear, iron studies, molecular gene testing, CBC blood test and erythrocyte protoporphyrin evaluation test.
HOW IS SIDEROBLASTIC ANEMIA TREATED?
Treatment depends on the cause of the sideroblastic anemia. Vitamin B6 (pyridoxine) therapy may be helpful in some cases. To remove excess iron from the body of someone with sideroblastic anemia, the drug desferrioxamine (Desferal) is infused under the skin (subcutaneously) or injected into a muscle (intramuscular), often with good results
DID YOU KNOW?
In severe cases of sideroblastic anaemia, the increased levels of iron in the blood may lead to heart disease, liver damage, and kidney failure.